Let's make this birthday one to remember.

49 years old (Born on December 12, 1975)

Happy birthday, Mayim Bialik! From your iconic hats and quirky charm as Blossom to becoming everyone's favorite neuroscientist on "The Big Bang Theory," you've proven that brains and humor are the perfect combo. Your ability to juggle acting, neuroscience expertise, hosting Jeopardy!, and still make us laugh is truly impressive—seriously, do you ever sleep?

Here's wishing you another year filled with laughter, success, and maybe fewer awkward moments explaining complicated science jokes at parties. Keep inspiring us all by proving smart really is the new cool—and please never stop reminding Sheldon Cooper who's boss. Happy Birthday!