Let's make this birthday one to remember.

45 years old (Born on June 23, 1980)

Happy Birthday to the hilarious Melissa Rauch, whose comedic genius as Bernadette Rostenkowski-Wolowitz kept science (and Howard Wolowitz!) wonderfully amusing on "The Big Bang Theory." Your spirited portrayal of Bernie's feisty wit, pint-sized but powerful energy, and unforgettable squeaky voice made us laugh until we cried. Who knew microbiology could be so entertaining?

Whether it's brilliantly chastising Sheldon or sweetly dominating Howard with sass-filled perfection, your performances have given audiences countless laughs — and priceless memes! Today we celebrate you: funny lady extraordinaire, amazing actress, and queen of comic timing. May your birthday be more fun than a Klingon Scrabble match!